| | |
| | |
Stat |
Members: 3645 Articles: 2'500'096 Articles rated: 2609
18 April 2024 |
|
| | | |
|
Article overview
| |
|
The genome sequence of Schizosaccharomyces pombe | V Wood
; R Gwilliam
; M-A Rajandream
; M Lyne
; R Lyne
; A Stewart
; J Sgouros
; N Peat
; J Hayles
; S Baker
; D Basham
; S Bowman
; K Brooks
; D Brown
; S Brown
; T Chillingworth
; C Churcher
; M Collins
; R Connor
; A Cronin
; P Davis
; T Feltwell
; A Fraser
; S Gentles
; A Goble
; N Hamlin
; D Harris
; J Hidalgo
; G Hodgson
; S Holroyd
; T Hornsby
; S Howarth
; E J Huckle
; S Hunt
; K Jagels
; K James
; L Jones
; M Jones
; S Leather
; S McDonald
; J McLean
; P Mooney
; S Moule
; K Mungall
; L Murphy
; D Niblett
; C Odell
; K Oliver
; S O’Neil
; D Pearson
; M A Quail
; E Rabbinowitsch
; K Rutherford
; S Rutter
; D Saunders
; K Seeger
; S Sharp
; J Skelton
; M Simmonds
; R Squares
; S Squares
; K Stevens
; K Taylor
; R G Taylor
; A Tivey
; S Walsh
; T Warren
; S Whitehead
; J Woodward
; G Volckaert
; R Aert
; J Robben
; B Grymonprez
; I Weltjens
; E Vanstreels
; M Rieger
; M Schäfer
; S Müller-Auer
; C Gabel
; M Fuchs
; A Düsterhöft
; C Fritzc
; E Holzer
; D Moestl
; H Hilbert
; K Borzym
; I Langer
; A Beck
; H Lehrach
; R Reinhardt
; T M Pohl
; P Eger
; W Zimmermann
; H Wedler
; R Wambutt
; B Purnelle
; A Goffeau
; E Cadieu
; S Dréano
; S Gloux
; V Lelaure
; S Mottier
; F Galibert
; S J Aves
; Z Xiang
; C Hunt
; K Moore
; S M Hurst
; M Lucas
; M Rochet
; C Gaillardin
; V A Tallada
; A Garzon
; G Thode
; R R Daga
; L Cruzado
; J Jimenez
; M Sánchez
; F del Rey
; J Benito
; A Domínguez
; J L Revuelta
; S Moreno
; J Armstrong
; S L Forsburg
; L Cerutti
; T Lowe
; W R McCombie
; I Paulsen
; J Potashkin
; G V Shpakovski
; D Ussery
; B G Barrell
; P Nurse
; L Cerrutti
; | Date: |
21 Feb 2002 | Journal: | Nature, 415 (6874), 871-80 | Abstract: | We have sequenced and annotated the genome of fission yeast (Schizosaccharomyces pombe), which contains the smallest number of protein-coding genes yet recorded for a eukaryote: 4,824. The centromeres are between 35 and 110 kilobases (kb) and contain related repeats including a highly conserved 1.8-kb element. Regions upstream of genes are longer than in budding yeast (Saccharomyces cerevisiae), possibly reflecting more-extended control regions. Some 43% of the genes contain introns, of which there are 4,730. Fifty genes have significant similarity with human disease genes; half of these are cancer related. We identify highly conserved genes important for eukaryotic cell organization including those required for the cytoskeleton, compartmentation, cell-cycle control, proteolysis, protein phosphorylation and RNA splicing. These genes may have originated with the appearance of eukaryotic life. Few similarly conserved genes that are important for multicellular organization were identified, suggesting that the transition from prokaryotes to eukaryotes required more new genes than did the transition from unicellular to multicellular organization. | Source: | PubMed, pmid11859360 doi: 10.1038/nature724 | Services: | Forum | Review | Favorites |
|
|
No review found.
Did you like this article?
Note: answers to reviews or questions about the article must be posted in the forum section.
Authors are not allowed to review their own article. They can use the forum section.
browser claudebot
|
| |
|
|
|
| News, job offers and information for researchers and scientists:
| |