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29 March 2024
 
  » pubmed » pmid2666863

 Article overview


Association of class I major histocompatibility heavy and light chains induced by viral peptides
A Townsend ; C Ohlén ; J Bastin ; H G Ljunggren ; L Foster ; K Kärre ;
Date 10 Aug 1989
Journal Nature, 340 (6233), 443-8
AbstractWe describe a cell in which association of a major histocompatibility complex class I heavy chain with beta 2-microglobulin is induced by a peptide derived from influenza nucleoprotein. Association of antigenic peptides with the binding site of class I molecules may be required for correct folding of the heavy chain, association with beta 2-microglobulin and transport of the antigen-MHC complex to the cell surface.
Source PubMed, pmid2666863 doi: 10.1038/340443a0
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