| | |
| | |
Stat |
Members: 3645 Articles: 2'503'724 Articles rated: 2609
23 April 2024 |
|
| | | |
|
Article overview
| |
|
Appearance of water channels in Xenopus oocytes expressing red cell CHIP28 protein | G M Preston
; T P Carroll
; W B Guggino
; P Agre
; | Date: |
17 Apr 1992 | Journal: | Science, 256 (5055), 385-7 | Abstract: | Water rapidly crosses the plasma membrane of red blood cells (RBCs) and renal tubules through specialized channels. Although selective for water, the molecular structure of these channels is unknown. The CHIP28 protein is an abundant integral membrane protein in mammalian RBCs and renal proximal tubules and belongs to a family of membrane proteins with unknown functions. Oocytes from Xenopus laevis microinjected with in vitro-transcribed CHIP28 RNA exhibited increased osmotic water permeability; this was reversibly inhibited by mercuric chloride, a known inhibitor of water channels. Therefore it is likely that CHIP28 is a functional unit of membrane water channels. | Source: | PubMed, pmid1373524 | Services: | Forum | Review | Favorites |
|
|
No review found.
Did you like this article?
Note: answers to reviews or questions about the article must be posted in the forum section.
Authors are not allowed to review their own article. They can use the forum section.
browser Mozilla/5.0 AppleWebKit/537.36 (KHTML, like Gecko; compatible; ClaudeBot/1.0; +claudebot@anthropic.com)
|
| |
|
|
|
| News, job offers and information for researchers and scientists:
| |