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25 April 2024

» pubmed » pmid7134966

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Damage to hypothalamic dopaminergic neurons is associated with development of prolactin-secreting pituitary tumors
D K Sarkar ; P E Gottschall ; J Meites ;
Date:	12 Nov 1982
Journal:	Science, 218 (4573), 684-6
Abstract:	Old female rats with spontaneous prolactin-secreting pituitary tumors (prolactinomas) and young females with prolactinomas produced by prolonged estrogen treatment had damaged tuberoinfundibular dopaminergic neurons. Since these neurons inhibit the function of pituitary prolactin-secreting cells, their destruction may lead to development of prolactinomas.
Source:	PubMed, pmid7134966
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