| | |
| | |
Stat |
Members: 3645 Articles: 2'504'928 Articles rated: 2609
25 April 2024 |
|
| | | |
|
Article overview
| |
|
Chronotypic action of theophylline and of pentobarbital as circadian zeitgebers in the rat | C F Ehret
; V R Potter
; K W Dobra
; | Date: |
20 Jun 1975 | Journal: | Science, 188 (4194), 1212-5 | Abstract: | In the rat the deep body temperature rhythm, monitored by telemetry, can be reset in a predictable direction by a stimulant (theopylline) and by a depressant (pentobarbital). When the drugs are applied immediately before or during the early active phases of the circadian cycle, the rhythm is set back (phase delay). When applied later, past the thermal peak, theophylline, but not pentobarbital, shifts the rhythm ahead (phase advance). Theophylline and pentobarbital in addition to having a number of already established pharmacological properties are now further identified as chronobiotics: they are drugs that may be used to alter the biological time structure by rephasing a circadian rhythm. | Source: | PubMed, pmid1145192 | Services: | Forum | Review | Favorites |
|
|
No review found.
Did you like this article?
Note: answers to reviews or questions about the article must be posted in the forum section.
Authors are not allowed to review their own article. They can use the forum section.
browser Mozilla/5.0 AppleWebKit/537.36 (KHTML, like Gecko; compatible; ClaudeBot/1.0; +claudebot@anthropic.com)
|
| |
|
|
|
| News, job offers and information for researchers and scientists:
| |