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Codon recognition by enzymatically mischarged valine transfer ribonucleic acid | | D Grunberger
; I B Weinstein
; K B Jacobson
; | | Date: |
26 Dec 1969 | | Journal: | Science, 166 (913), 1635-7 | | Abstract: | Direct evidence for the adaptor hypothesis has been obtained by examining the codon recognition of a purified Escherichia coli valine transfer ribonucleic acid which was enzymatically mischarged with phenylalanine labeled with carbn-14 by reaction with purified phenylalanyl-transfer ribonucleic acid synthetase from Neurospora crassa. The mischarged transfer ribonucleic acid recognized the valine codons but failed to recognize the phenylalanine codon when tested in trinucleotide-directed ribosomal binding assay. | | Source: | PubMed, pmid4902680 | | Services: | Forum | Review | Favorites | |
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