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Coupled dynamics of voltage and calcium in paced cardiac cells | Yohannes Shiferaw
; Daisuke Sato
; Alain Karma
; | Date: |
31 Jan 2005 | Journal: | Phys Rev E, 71 (2 Pt 1), 021903 | Abstract: | We investigate numerically and analytically the coupled dynamics of transmembrane voltage and intracellular calcium cycling in paced cardiac cells using a detailed physiological model, and its reduction to a three-dimensional discrete map. The results provide a theoretical framework to interpret various experimentally observed modes of instability ranging from electromechanically concordant and discordant alternans to quasiperiodic oscillations of voltage and calcium. | Source: | PubMed, pmid15783348 | Other source: | [GID 182746] physics/0405048 | Services: | Forum | Review | Favorites |
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