| | |
| | |
Stat |
Members: 3645 Articles: 2'501'711 Articles rated: 2609
19 April 2024 |
|
| | | |
|
Article overview
| |
|
Translocation of a Single Stranded DNA Through a Conformationally Changing Nanopore | O. Flomenbom
; J. Klafter
; | Date: |
11 Aug 2003 | Journal: | Biophys. J. 86: 3576-3584 (2004) DOI: 10.1529/biophysj.103.037580 | Subject: | Statistical Mechanics; Soft Condensed Matter; Subcellular Processes | cond-mat.stat-mech cond-mat.soft q-bio.SC | Abstract: | We investigate the translocation of a single stranded DNA through a pore which fluctuates between two conformations, using coupled master equations. The probability density function of the first passage times (FPT) of the translocation process is calculated, displaying a triple, double or mono peaked behavior, depending on the interconversion rates between the conformations, the applied electric field, and the initial conditions. The cumulative probability function of the FPT, in a field-free environment, is shown to have two regimes, characterized by fast and slow timescales. An analytical expression for the mean first passage time of the translocation process is derived, and provides, in addition to the interconversion rates, an extensive characterization of the translocation process. Relationships to experimental observations are discussed. | Source: | arXiv, cond-mat/0308199 | Services: | Forum | Review | PDF | Favorites |
|
|
No review found.
Did you like this article?
Note: answers to reviews or questions about the article must be posted in the forum section.
Authors are not allowed to review their own article. They can use the forum section.
browser Mozilla/5.0 AppleWebKit/537.36 (KHTML, like Gecko; compatible; ClaudeBot/1.0; +claudebot@anthropic.com)
|
| |
|
|
|
| News, job offers and information for researchers and scientists:
| |