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29 March 2024
 
  » arxiv » 1504.6463

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The dichotomy structure of Y chromosome Haplogroup N
Kang Hu ; Shi Yan ; Kai Liu ; Chao Ning ; Lan-Hai Wei ; Shi-Lin Li ; Bing Song ; Ge Yu ; Feng Chen ; Li-Jun Liu ; Zhi-Peng Zhao ; Chuan-Chao Wang ; Ya-Jun Yang ; Zhen-Dong Qin ; Jing-Ze Tan ; Fu-Zhong Xue ; Hui Li ; Long-Li Kang ; Li Jin ;
Date 24 Apr 2015
AbstractHaplogroup N-M231 of human Y chromosome is a common clade from Eastern Asia to Northern Europe, being one of the most frequent haplogroups in Altaic and Uralic-speaking populations. Using newly discovered bi-allelic markers from high-throughput DNA sequencing, we largely improved the phylogeny of Haplogroup N, in which 16 subclades could be identified by 33 SNPs. More than 400 males belonging to Haplogroup N in 34 populations in China were successfully genotyped, and populations in Northern Asia and Eastern Europe were also compared together. We found that all the N samples were typed as inside either clade N1-F1206 (including former N1a-M128, N1b-P43 and N1c-M46 clades), most of which were found in Altaic, Uralic, Russian and Chinese-speaking populations, or N2-F2930, common in Tibeto-Burman and Chinese-speaking populations. Our detailed results suggest that Haplogroup N developed in the region of China since the final stage of late Paleolithic Era.
Source arXiv, 1504.6463
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