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Bi-Phasic Vesicles: instability induced by adsorption of proteins | | Jean-Marc Allain
; Martine Ben Amar
; | | Date: |
18 Dec 2003 | | Subject: | Subcellular Processes | q-bio.SC | | Abstract: | The recent discovery of a lateral organization in cell membranes due to small structures called ’rafts’ has motivated a lot of biological and physico-chemical studies. A new experiment on a model system has shown a spectacular budding process with the expulsion of one or two rafts when one introduces proteins on the membrane. In this paper, we give a physical interpretation of the budding of the raft phase. An approach based on the energy of the system including the presence of proteins is used to derive a shape equation and to study possible instabilities. This model shows two different situations which are strongly dependent on the nature of the proteins: a regime of easy budding when the proteins are strongly coupled to the membrane and a regime of difficult budding. | | Source: | arXiv, q-bio.SC/0312028 | | Services: | Forum | Review | PDF | Favorites | |
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