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Magnetic resonance force microscopy with a one-dimensional resolution of 0.9 nanometers | | U. Grob
; M. D. Krass
; M. Héritier
; R. Pachlatko
; J. Rhensius
; J. Košata
; B. A. Moores
; H. Takahashi
; A. Eichler
; C. L. Degen
; | | Date: |
12 Aug 2019 | | Abstract: | Magnetic resonance force microscopy (MRFM) is a scanning probe technique
capable of detecting MRI signals from nanoscale sample volumes, providing a
paradigm-changing potential for structural biology and medical research. Thus
far, however, experiments have not reached suffcient spatial resolution for
retrieving meaningful structural information from samples. In this work, we
report MRFM imaging scans demonstrating a resolution of 0.9 nm and a
localization precision of 0.6 nm in one dimension. Our progress is enabled by
an improved spin excitation protocol furnishing us with sharp spatial control
on the MRFM imaging slice, combined with overall advances in instrument
stability. From a modeling of the slice function, we expect that our
arrangement supports spatial resolutions down to 0.3 nm given suffcient
signal-to-noise ratio. Our experiment demonstrates the feasibility of
sub-nanometer MRI and realizes an important milestone towards the
three-dimensional imaging of macromolecular structures. | | Source: | arXiv, 1908.4180 | | Services: | Forum | Review | PDF | Favorites | |
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