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20 April 2024
 
  » arxiv » 1909.8421

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Reduction and Hamiltonian aspects of a model for virus-tumour interaction in oncolytic virotherapy
Anindya Ghose-Choudhury ; Partha Guha ;
Date 17 Sep 2019
AbstractWe analyse the Hamiltonian structure of a system of first-order ordinary differential equations used for modeling the interaction of an oncolytic virus with a tumour cell population. The analysis is based on the existence of a Jacobi Last Multiplier for the system and a time dependent first integral. For suitable conditions on the model parameters this allows for the reduction of the problem to a planar system of equations for which the time dependent Hamiltonian flows are described. The geometry of the Hamiltonian flows are finally investigated using the symplectic and cosymplectic methods.
Source arXiv, 1909.8421
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