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20 April 2024
 
  » arxiv » cond-mat/0401624

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The helix--coil transition on the worm--like chain
Alex J. Levine ;
Date 30 Dec 2003
Subject Soft Condensed Matter | cond-mat.soft
AbstractI propose a variation of the standard worm--like chain model to account for internal order parameter (helix/coil) fields on the polymer chain. This internal order parameter field influences polymer conformational statistics by locally modifying the persistence length of the chain. Using this model, I make predictions for the bending and stretching response of an alpha-helical domain of a protein. In particular, I show that alpha-helical protein domains will buckle under applied torque. This highly nonlinear elastic behavior may be important in the understanding of allosteric control of biochemical pathways.
Source arXiv, cond-mat/0401624
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