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19 April 2024
 
  » arxiv » q-bio.QM/0411033

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An Information-Theoretic Approach to Network Modularity
Etay Ziv ; Manuel Middendorf ; Chris Wiggins ;
Date 16 Nov 2004
Subject Quantitative Methods; Genomics; Molecular Networks | q-bio.QM q-bio.GN q-bio.MN
Affiliation1 and 2 and 6), Manuel Middendorf (3 and 6), Chris Wiggins (4 and 5) ( College of Physicians & Surgeons, Department of Biomedical Engineering, Department of Physics, Department of Applied Physics and Applied Mathematics, Center for Computational Bi
AbstractExploiting recent developments in information theory, we propose, illustrate, and validate a principled information-theoretic algorithm for module discovery and resulting measure of network modularity. This measure is an order parameter (a dimensionless number between 0 and 1). Comparison is made to other approaches to module-discovery and to quantifying network modularity using Monte Carlo generated Erdos-like modular networks. Finally, the Network Information Bottleneck (NIB) algorithm is applied to a number of real world networks, including the "social" network of coauthors at the APS March Meeting 2004.
Source arXiv, q-bio.QM/0411033
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