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20 April 2024
 
  » arxiv » q-bio.SC/0501014

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Single Stranded DNA Translocation Through a Fluctuating Nanopore
O. Flomenbom ; J. Klafter ;
Date 12 Dec 2004
Journal J.T. Fourkas, P. Levitz, M. Urbakh, K.J. Wahl Eds. Dynamics in Small Confining Systems, MRS Proceedings (Boston, 2003)
Subject Subcellular Processes; Soft Condensed Matter | q-bio.SC cond-mat.soft
AbstractWe investigate the translocation of a single stranded DNA (ssDNA) through a pore, which fluctuates between two conformations, by using coupled master equations (ME). The probability density function (PDF) of the first passage times (FPT) of the translocation process is calculated, displaying a triple, double or mono-peaked behavior, depending on the system parameters. An analytical expression for the mean first passage time (MFPT) of the translocation process is derived, and provides an extensive characterization of the translocation process.
Source arXiv, q-bio.SC/0501014
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