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29 March 2024
 
  » arxiv » q-bio.TO/0504009

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Dynamics of conduction blocks in a model of paced cardiac tissue
Herve Henry ; Wouter-Jan Rappel ;
Date 6 Apr 2005
Subject Tissues and Organs; Other; Biological Physics; Pattern Formation and Solitons | q-bio.TO cond-mat.other nlin.PS physics.bio-ph q-bio.OT
AbstractWe study numerically the dynamics of conduction blocks using a detailed electrophysiological model. We find that this dynamics depends critically on the size of the paced region. Small pacing regions lead to stationary conduction blocks while larger pacing regions can lead to conduction blocks that travel periodically towards the pacing region. We show that this size-dependence dynamics can lead to a novel arrhythmogenic mechanism. Furthermore, we show that the essential phenomena can be captured in a much simpler coupled-map model.
Source arXiv, q-bio.TO/0504009
Other sources [GID 803809] q-bio.TO/0504009 pmid16089575
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