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Evolutionary origin of power-laws in Biochemical Reaction Network; embedding abundance distribution into topology | | Chikara Furusawa
; Kunihiko Kaneko
; | | Date: |
28 Apr 2005 | | Subject: | Populations and Evolution; Molecular Networks | q-bio.PE q-bio.MN | | Abstract: | The evolutionary origin of universal statistics in biochemical reaction network is studied, to explain the power-law distribution of reaction links and the power-law distributions of chemical abundances. Using cell models with catalytic reaction network, we find evidence that the power-law distribution in abundances of chemicals emerges by the selection of cells with higher growth speeds. Through the further evolution, this inhomogeneity in chemical abundances is shown to be embedded in the distribution of links, leading to the power-law distribution. These findings provide novel insights into the nature of network evolution in living cells. | | Source: | arXiv, q-bio.PE/0504032 | | Services: | Forum | Review | PDF | Favorites | |
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