| | |
| | |
Stat |
Members: 3645 Articles: 2'501'711 Articles rated: 2609
19 April 2024 |
|
| | | |
|
Article overview
| |
|
Detection of confinement and jumps in single molecule membrane trajectories | N. Meilhac
; L. Le Guyader
; L. Salome
; N. Destainville
; | Date: |
20 Jul 2005 | Subject: | Quantitative Methods; Subcellular Processes; Statistical Mechanics | q-bio.QM cond-mat.stat-mech q-bio.SC | Abstract: | We propose a novel variant of the algorithm by Simson et al. [Simson et al., Biophys. J. 69, 989 (1995)]. Their algorithm was developed to detect transient confinement zones in experimental single particle tracking trajectories of diffusing membrane proteins or lipids. We show that our algorithm is able to detect confinement in a wider class of confining potential shapes than Simson et al.’s one. Furthermore it enables to detect not only temporary confinement but also jumps between confinement zones. Jumps are predicted by membrane skeleton fence and picket models. In the case of experimental trajectories of $mu$-opioid receptors, which belong to the family of G-protein-coupled receptors involved in a signal transduction pathway, this algorithm confirms that confinement cannot be explained solely by rigid fences. | Source: | arXiv, q-bio.QM/0507031 | Services: | Forum | Review | PDF | Favorites |
|
|
No review found.
Did you like this article?
Note: answers to reviews or questions about the article must be posted in the forum section.
Authors are not allowed to review their own article. They can use the forum section.
browser Mozilla/5.0 AppleWebKit/537.36 (KHTML, like Gecko; compatible; ClaudeBot/1.0; +claudebot@anthropic.com)
|
| |
|
|
|
| News, job offers and information for researchers and scientists:
| |