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19 April 2024

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Brownian Dynamics Simulation of Nucleosome Formation and Disruption under Stretching
Wei Li ; Shuo-Xing Dou ; Peng-Ye Wang ;
Date:	23 Dec 2003
Journal:	Journal of Theoretical Biology 230 (2004) 375-383
Subject:	Biomolecules \| q-bio.BM
Abstract:	Using a Brownian dynamics simulation, we numerically studied the interaction of DNA with histone and proposed an octamer-rotation model to describe the process of nucleosome formation. Nucleosome disruption under stretching was also simulated. The theoretical curves of extension versus time as well as of force versus extension are consistent with previous experimental results.
Source:	arXiv, q-bio.BM/0312036
Services:	Forum \| Review \| PDF \| Favorites

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