| | |
| | |
Stat |
Members: 3667 Articles: 2'599'751 Articles rated: 2609
07 February 2025 |
|
| | | |
|
Article overview
| |
|
Shaped two-photon excitation deep inside scattering tissue | Eirini Papagiakoumou
; Aurélien Bègue
; Osip Schwartz
; Dan Oron
; Valentina Emiliani
; | Date: |
1 Sep 2011 | Abstract: | Light is the tool of the 21st century. New photosensitive tools offer the
possibility to monitor and control neuronal activity from the sub-cellular to
the integrative level. This ongoing revolution has motivated the development of
new optical methods for light stimulation. Among them, it has been recently
demonstrated that a promising approach is based on the use of wavefront shaping
to generate optically confined extended excitation patterns. This was achieved
by combining the technique of temporal focusing with different approaches for
lateral light shaping including low numerical aperture Gaussian beams,
holographic beams and beams created with the generalized phase contrast mthod.
What is needed now is a precise characterization of the effect of scattering on
hese different methods in order to extend their use for in depth excitation.
Here we present a theoretical and experimental study on the effect of
scattering on the propagation of wavefront shaped beams. Results from fixed and
acute cortical slices show that temporally focused spatial patterns are
extremely robust against the effects of scattering and this permits their
three-dimensional confinement for depths up to 550 {mu}m. | Source: | arXiv, 1109.0160 | Services: | Forum | Review | PDF | Favorites |
|
|
No review found.
Did you like this article?
Note: answers to reviews or questions about the article must be posted in the forum section.
Authors are not allowed to review their own article. They can use the forum section.
|
| |
|
|
|