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Article overview
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Quantum correlation enhanced super-resolution localization microscopy | Yonatan Israel
; Ron Tenne
; Dan Oron
; Yaron Silberberg
; | Date: |
1 Sep 2016 | Abstract: | In standard localization microscopy methods a small number of emitters are
sparsely photoswitched, typically not more than one flourophore per diffraction
limited spot, limiting the temporal resolution of super-resolved images.
Localization of a non-sparse scene requires a precise estimate for the number
of active emitters. Quantum correlations in the emitted fluorescence can probe
the number of activated emitters, exploiting the fact that a single fluorophore
emits a single photon at a time. To obtain this additional information, which
is not provided by conventional cameras, we employ a new imaging configuration
based on single-photon avalanche detectors (SPAD). Here we demonstrate a 20nm
resolution localization and single-particle tracking (SPT) of non-sparsely
activated emitters, which may facilitate super-resolved imaging at enhanced
temporal resolution. | Source: | arXiv, 1609.0312 | Services: | Forum | Review | PDF | Favorites |
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