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Simulation studies of a phenomenological model for elongated virus capsid formation | | Ting Chen
; Sharon C. Glotzer
; PDF only
; | | Date: |
6 Jan 2007 | | Subject: | Soft Condensed Matter; Materials Science | | Abstract: | We study a phenomenological model in which the simulated packing of hard, attractive spheres on a prolate spheroid surface with convexity constraints produces structures identical to those of prolate virus capsid structures. Our simulation approach combines the traditional Monte Carlo method with a modified method of random sampling on an ellipsoidal surface and a convex hull searching algorithm. Using this approach we identify the minimum physical requirements for non-icosahedral, elongated virus capsids, such as two aberrant flock house virus (FHV) particles and the prolate prohead of bacteriophage $phi_{29}$, and discuss the implication of our simulation results in the context of recent experimental findings. Our predicted structures may also be experimentally realized by evaporation-driven assembly of colloidal spheres. | | Source: | arXiv, cond-mat/0701125 | | Services: | Forum | Review | PDF | Favorites | |
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