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12 February 2025
 
  » pubmed » pmid2983431

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A region of the Herpesvirus saimiri genome required for oncogenicity
R C Desrosiers ; A Bakker ; J Kamine ; L A Falk ; R D Hunt ; N W King ;
Date 12 Apr 1985
Journal Science, 228 (4696), 184-7
AbstractHerpesvirus saimiri naturally infects squirrel monkeys (Saimiri sciureus) without producing signs of disease; infection of other New World primates, however, results in a rapidly progressing, malignant, T-cell lymphoma. Results described in this report identify a region of the viral genome that is required for oncogenicity in owl monkeys (Aotus trivirgatus); this region is not required for replication of the virus. This is believed to be the first such genomic region identified in a herpesvirus system.
Source PubMed, pmid2983431
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