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Article overview
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A region of the Herpesvirus saimiri genome required for oncogenicity | R C Desrosiers
; A Bakker
; J Kamine
; L A Falk
; R D Hunt
; N W King
; | Date: |
12 Apr 1985 | Journal: | Science, 228 (4696), 184-7 | Abstract: | Herpesvirus saimiri naturally infects squirrel monkeys (Saimiri sciureus) without producing signs of disease; infection of other New World primates, however, results in a rapidly progressing, malignant, T-cell lymphoma. Results described in this report identify a region of the viral genome that is required for oncogenicity in owl monkeys (Aotus trivirgatus); this region is not required for replication of the virus. This is believed to be the first such genomic region identified in a herpesvirus system. | Source: | PubMed, pmid2983431 | Services: | Forum | Review | Favorites |
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