| | |
| | |
Stat |
Members: 3667 Articles: 2'599'751 Articles rated: 2609
17 February 2025 |
|
| | | |
|
Article overview
| |
|
Sequence of the alpha subunit of photoreceptor G protein: homologies between transducin, ras, and elongation factors | M A Lochrie
; J B Hurley
; M I Simon
; | Date: |
5 Apr 1985 | Journal: | Science, 228 (4695), 96-9 | Abstract: | A bovine retinal complementary DNA clone encoding the alpha subunit of transducin (T alpha) was isolated with the use of synthetic oligodeoxynucleotides as probes, and the complete nucleotide sequence of the insert was determined. THe predicted protein sequence of 354 amino acids includes the known sequences of four tryptic peptides and sequences adjacent to the residues that undergo adenosine diphosphate ribosylation by cholera toxin and pertussis toxin. On the basis of homologies to other proteins, such as the elongation factors of protein synthesis and the ras oncogene proteins, regions are identified that are predicted to be acylated and involved in guanine nucleotide binding and hydrolysis. Amino acid sequence similarity between T alpha and ras is confined to these regions of the molecules. | Source: | PubMed, pmid3856323 | Services: | Forum | Review | Favorites |
|
|
No review found.
Did you like this article?
Note: answers to reviews or questions about the article must be posted in the forum section.
Authors are not allowed to review their own article. They can use the forum section.
|
| |
|
|
|