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19 April 2024 |
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Morphine and ethanol: selective depletion of regional brain calcium | | D H Ross
; M A Medina
; H L Cardenas
; | | Date: |
4 Oct 1974 | | Journal: | Science, 186 (4158), 63-5 | | Abstract: | Administration of morphine or ethanol to rats produces a decrease in regional brain calcium in vivo. This effect is selectively antagonized by the stereospecific narcotic antagonist naloxone. Reserpine and the dopamine-acetaldehyde conjugate salsolinol also produce a depletion of regional brain calcium, but only the salsolinol depletion is antagonized by naloxone. Experiments with naloxone provide evidence for two calcium-sensitive pools in the central nervous system. | | Source: | PubMed, pmid4420821 | | Services: | Forum | Review | Favorites | |
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