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Requirement of a small cytoplasmic RNA for the establishment of thermotolerance | | P A Fung
; J Gaertig
; M A Gorovsky
; R L Hallberg
; | | Date: |
19 May 1995 | | Journal: | Science, 268 (5213), 1036-9 | | Abstract: | Thermotolerance is an inducible state that endows cells with an enhanced resistance to thermal killing. Heat shock proteins are believed, and in a few instances have been shown, to be the agents conferring this resistance. The role of a small cytoplasmic RNA (G8 RNA) in developing thermotolerance in Tetrahymena thermophila was investigated by creating a strain devoid of all functional G8 genes. These G8 null cells mounted an apparently normal heat shock response, but they were unable to establish thermotolerance. | | Source: | PubMed, pmid7754381 | | Services: | Forum | Review | Favorites | |
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