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27 April 2024

» pubmed » pmid210392

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Epidemiological evidence for causal relationship between Epstein-Barr virus and Burkitt's lymphoma from Ugandan prospective study
G de-Thé ; A Geser ; N E Day ; P M Tukei ; E H Williams ; D P Beri ; P G Smith ; A G Dean ; G W Bronkamm ; P Feorino ; W Henle ;
Date:	24 Aug 1978
Journal:	Nature, 274 (5673), 756-61
Abstract:	Results from a prospective sero-epidemiological study initiated in Uganda in 1971 indicate that children with high antibody titres to Epstein-Barr virus structural antigens are at high risk of developing Burkitt’s lymphoma. These findings strongly support a causal relationship between the Epstein-Barr virus and Burkitt’s lymphoma but suggest that the oncogenic potential of the virus is realised only in exceptional circumstances.
Source:	PubMed, pmid210392
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