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Article overview
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Familial imprinting determines H-2 selective mating preferences | K Yamazaki
; G K Beauchamp
; D Kupniewski
; J Bard
; L Thomas
; E A Boyse
; | Date: |
3 Jun 1988 | Journal: | Science, 240 (4857), 1331-2 | Abstract: | Inbred male mice typically prefer to mate with females of a different, non-self H-2 haplotype. To determine whether this natural preference is irrevocable or results from familial imprinting, a test system was used which relied on previous observations that B6 males (H-2b) mate preferentially with congenic B6-H-2k rather than B6 females, and B6-H-2k males with B6 females. This preference was reversed in B6 males fostered by B6-H-2k parents and in B6-H-2k males fostered by B6 parents, preference in these cases favoring the same H-2 type. Thus, H-2 selective mating preference is acquired by imprinting on familial H-2 types. | Source: | PubMed, pmid3375818 | Services: | Forum | Review | Favorites |
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