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26 April 2024
 
  » pubmed » pmid6857281

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Recognition of H-2 types in relation to the blocking of pregnancy in mice
K Yamazaki ; G K Beauchamp ; C J Wysocki ; J Bard ; L Thomas ; E A Boyse ;
Date 8 Jul 1983
Journal Science, 221 (4606), 186-8
AbstractInbred BALB/c females were mated and subsequently exposed in a divided cage to "stimulus" males or females whose H-2 type was similar or dissimilar to the stud male’s. The incidence of pregnancy blocking was considerably higher when stud and stimulus males differed in H-2 type than when they did not. Similar results were obtained with urine samples of H-2 identical and nonidentical males. Females exposed after mating to other females whose H-2 type differed from the stud male, under the same experimental conditions, also showed an appreciable incidence of pregnancy block. It is therefore concluded that chemosensory recognition of H-2 types affects the reproductive hormonal status of the pregnant female.
Source PubMed, pmid6857281
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