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Chicken gizzard: relation between calcium-activated phosphorylation and contraction | | P E Hoar
; W G Kerrick
; P S Cassidy
; | | Date: |
4 May 1979 | | Journal: | Science, 204 (4392), 503-6 | | Abstract: | Of the proteins in mechanically disrupted chicken gizzard fibers (no functional sarcolemma) only the 20,000-dalton light chains of myosin underwent large Ca2+-and Sr2+-dependent changes in phosphorylation. Phosphorylation closely corresponded with the Ca2+- and Sr2+-activated tensions. Adenosine 5’-O (3’-thiotriphosphate) only in the presence of Ca2+ induced irreversible Ca2+-insensitive activation of tension and thiophosphorylation of the 20,000-dalton light chains, and blocked incorporation of 32P from [gamma-32P]adenosine triphosphate into the myosin light chains. | | Source: | PubMed, pmid432654 | | Services: | Forum | Review | Favorites | |
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