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27 April 2024
 
  » arxiv » cond-mat/0406028

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Bubble Relaxation Dynamics in Double-Stranded DNA
D. J. Bicout ; E. Kats ;
Date 1 Jun 2004
Subject Soft Condensed Matter; Statistical Mechanics | cond-mat.soft cond-mat.stat-mech
Affiliation1,2) and E. Kats (1,3) (1 - Institut Laue-Langevin, Grenoble, France; 2 - Biomathematics and Epidemiology, ENVL, Marcy l’Etoile, France; 3 - L. D. Landau Institute for Theoretical Physics, RAS, Moscow, Russia.
AbstractThe paper deals with the two-state (opening-closing of base pairs) model used to describe the fluctuation dynamics of a single bubble formation. We present an exact solution for the discrete and finite size version of the model that includes end effects and derive analytic expressions of the correlation function, survival probability and lifetimes for the bubble relaxation dynamics. It is shown that the continuous and semi-infinite limit of the model becomes a good approximation to exact result when a^N << 1, where N is bubble size and a, the ratio of opening to closing rates of base pairs, is the control parameter of DNA melting.
Source arXiv, cond-mat/0406028
Other source [GID 420705] pmid15324035
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