|
| | | | |
| | | |
| Stat |
Members: 3647
Articles: 2'510'585
Articles rated: 2609
05 May 2024 |
|
| | | | |
|
Article overview
| |
|
|
Transforming growth factor-beta signaling in stem cells and cancer | | Lopa Mishra
; Rik Derynck
; Bibhuti Mishra
; | | Date: |
7 Oct 2005 | | Journal: | Science, 310 (5745), 68-71 | | Abstract: | Transforming growth factor-beta (TGF-beta) and TGF-beta-related proteins, such as the bone morphogenetic proteins, have emerged as key regulators of stem cell renewal and differentiation. These proteins have disparate roles in regulating the biology of embryonic stem cells and tumor suppression, and they help define the selection of cell fate and the progression of differentiation along a lineage. Here we illustrate their roles in embryonic stem cells and in the differentiation of neural, hematopoietic, mesenchymal, and gastrointestinal epithelial stem cells. | | Source: | PubMed, pmid16210527 doi: 10.1126/science.1118389 | | Services: | Forum | Review | Favorites | |
|
|
No review found.
Did you like this article?
Note: answers to reviews or questions about the article must be posted in the forum section.
Authors are not allowed to review their own article. They can use the forum section.
|
| |
|
|
|
REGISTER