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26 April 2024
 
  » pubmed » pmid4212918

 Article overview



Aldosterone-induced protein in toad urinary bladder
W B Benjamin ; I Singer ;
Date 18 Oct 1974
Journal Science, 186 (4160), 269-72
AbstractSimultaneous electrophysiological and biochemical experiments demonstrated a specific aldosterone-induced protein in paired urinary hemibladders isolated from the toad Bufo marinus. Whenever aldosterone stinlmulated short-circuit current, aldosterone specifically increased [(35)S] methionine incorporation into a low-molecular-weight protein (about 12,000). Comparative studies with dexamethasone and insulin and inhibitory studies with spironolactone and actinomycin D suggest mineralocorticoid specificity.
Source PubMed, pmid4212918
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