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Article overview
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Surface modification of T-lymphocytes observed during rosetting | | P S Lin
; D F Wallach
; | | Date: |
21 Jun 1974 | | Journal: | Science, 184 (143), 1300-1 | | Abstract: | Scanning electron microscopy has been used to characterize alterations of lymphocyte surface topology that occur on contact with erythrocytes during the rosetting reaction. Molt-4 cells, a line of leukemic human lymphocytes, defined as T-cells through their ability to form rosettes with sheep erythrocytes, were used for this. Unreacted Molt-4 cells exhibit surfaces that are virtually smooth and carry few microvilli. In contrast, Molt-4 cells in rosettes display a time-dependent modification of surface topology, characterized by the emergence of numerous, long microvilli, particularly in areas of red cell contact. | | Source: | PubMed, pmid4545419 | | Services: | Forum | Review | Favorites | |
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