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Zinc fingers in Caenorhabditis elegans: finding families and probing pathways | | N D Clarke
; J M Berg
; | | Date: |
11 Dec 1998 | | Journal: | Science, 282 (5396), 2018-22 | | Abstract: | More than 3 percent of the protein sequences inferred from the Caenorhabditis elegans genome contain sequence motifs characteristic of zinc-binding structural domains, and of these more than half are believed to be sequence-specific DNA-binding proteins. The distribution of these zinc-binding domains among the genomes of various organisms offers insights into the role of zinc-binding proteins in evolution. In addition, the complete genome sequence of C. elegans provides an opportunity to analyze, and perhaps predict, pathways of transcriptional regulation. | | Source: | PubMed, pmid9851917 | | Services: | Forum | Review | Favorites | |
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